Kanna, a succulent plant known for its small flowers usually in white or yellow hues, originally thrives in the Karoo Desert of South Africa. It continues to grow naturally in this region and is now increasingly cultivated for commercial purposes because of its medicinal benefits.

It last anywhere from 6 to 13 hours in the waking state and even up to 24 hours if the effects extend into a sleep cycle. The effects are more pronounced in the first 3 hours and gradually taper without the feeling of a crash due to Kanna's adaptogenic nature. Kanna is typically half out of the body within 24 to 27 hours and is 99% eliminated from the body within 2 to 4 days.

Based on the available research, Kanna ingestion is considered safe and well-tolerated for most people. Studies found no adverse effects on liver or kidney function and does not affect blood pressure or heart rate.

Additionally, Kanna has a long history of traditional daily use by the indigenous Khoisan people in southern Africa. Kanna is non habit-forming, non-addictive with no tolerance build-up.

However, scientific research on long-term Kanna use has not yet been conducted and individual experiences can vary. As with anything, it is advisable to pay attention to how your body responds and check with a medical professional if any health concerns arise from regular intake.

Although it will naturally help you relax, you’ll want to avoid taking them too close to bedtime since they do have an energizing and activating effect. Though every person is different. Try taking them earlier or lowering the dose if your desire is to wind down before hitting the hay.

MDMA (a.k.a. Ecstasy/Molly) is a synthetic drug that produces feelings of euphoria and empathy. This drug is known as a popular rave drug, but it can also be used in a therapeutic setting to treat PTSD and anxiety. Although Kanna is called natural MDMA by some, there are important differences between the two which should not be overlooked. The main similarity is that they both have a euphoric and heart-opening effect, but the similarity ends there. 

Unlike kanna, MDMA is synthetic, contains amphetamines, and is known to cause negative side effects such as memory problems, depression, and an increased risk of addiction. Kanna is neuro-protective while MDMA damages the neuroreceptor system in the brain. Serotonin can be depleted by taking MDMA but Kanna replenishes serotonin in your system. MDMA can also cause hyperthermia, which is a dangerous rise in body temperature that can lead to organ failure.